Part 1: Extracted from the White Paper "Secreted Matrix™ and Matrix NC-138™" by Michael Cohen
The combination of age, environmental factors and genetic component scan
contribute to changes in the appearance, viscoelastic properties and topography
of the skin, particularly of the face, changes which in many cultures are
considered undesirable if not pathologic. While such changes are usually
superficial and have no physical impact on the function of the body’s major
organs, manifestations on the face, neck and, to a lesser extent, the hands are
enduring targets for the application of myriad agents in an ongoing attempt to
effect a dramatic reversal or at least arresting the progression of the ravages of
time. Most attempts and agents are superficial, short term and ineffective.
During pregnancy, a woman’s body increases the production of specific proteins
in response to secretions produced by the embryo. These specific proteins effect
specific receptor in both fibroblasts and keratinocytes that increase the
production of collagen. Proteoderm has patented these secretions and
developed compositions including topical formulations comprising secreted
products obtained from the culture medium of human stem cell derivatives and
particular combinations of components thereof are provided for treatment of
various dermatological conditions, such as adverse consequences of aging,
wrinkling, altered pigmentation, altered viscoelasticity, and altered thickness,
among others. Further, Proteoderm has developed methods for using these
compositions and topical formulations for treating adverse or undesirable
dermatological conditions are also provided, as well as preventing the
appearance of undesirable dermatological conditions. Unlike injection of
collagen that occupies extracellular space Proteoderm methods and
product enhance the natural formation of collagen (Figure 1).

Figure 1
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